The effects of FK506 combined with natamycin in the treatment of experimental fungal keratitis by suppressing NLRP3 inflammasome activation:

Li Liang; Wei-Yun Shi

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The effects of FK506 combined with natamycin in the treatment of experimental fungal keratitis by suppressing NLRP3 inflammasome activation:

机译：FK506联合那他霉素通过抑制NLRP3炎性体活化来治疗实验性真菌性角膜炎：

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摘要

The aim of this study was to investigate the mechanisms of combination treatment with FK506 and natamycin on alleviating damage of the cornea in mouse model of fungal keratitis.

机译：这项研究的目的是研究与FK506和那他霉素联合治疗减轻真菌性角膜炎小鼠角膜损伤的机制。

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来源
《European Journal of Inflammation》 |2017年第3期|共页
作者
Li Liang; Wei-Yun Shi;
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中图分类基础医学;
关键词
corneal damageFK506fungal keratitisnatamycinNLRP3 inflammasome;

机译：角膜损伤FK506真菌性角膜炎纳他霉素NLRP3炎性体;

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专利

1. Tacrolimus interacts with voriconazole to reduce the severity of fungal keratitis by suppressing IFN-related inflammatory responses and concomitant FK506 and voriconazole treatment suppresses fungal keratitis [J] . Jing Zhong, Lulu Peng, Bowen Wang, Molecular vision . 2018,第1999期

机译：他克莫司与伏立康唑相互作用可通过抑制IFN相关的炎症反应来降低真菌性角膜炎的严重程度，同时伴随FK506和伏立康唑的治疗可抑制真菌性角膜炎
2. Combined Application of 5％ Natamycin and 0.2％ Fluconazole for the Treatment of Fungal Keratitis [J] . Hua Gong, Xiangming Gong 眼科学报（英文版） . 2013,第002期

机译：5％纳他霉素和0.2％氟康唑联合应用治疗真菌性角膜炎
3. Dimethyl fumarate ameliorates dextran sulfate sodium-induced murine experimental colitis by activating Nrf2 and suppressing NLRP3 inflammasome activation [J] . Liu Xiuting, Zhou Wei, Zhang Xin, Biochemical Pharmacology . 2016,第Null期

机译：富马酸二甲酯通过激活Nrf2和抑制NLRP3炎性体激活来改善硫酸葡聚糖钠诱导的鼠实验性结肠炎
4. Insights into Kinome Perturbation During NLRP3 Inflammasome Activation Using an Isotope-Coded ATP-affinity Probe and Targeted Mass Spectrometry [C] . Preston Williams, Yongsheng Xiao, Lei Guo, ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：使用同位素编码的ATP - 亲和探针和靶向质谱法在NLRP3炎症组活化期间洞察Kinome扰动
5. Complement Protein C1q Modulates Macrophage NLRP3 Inflammasome Activation. [D] . Manughian-Peter, Ayla. 2018

机译：补体蛋白C1q调节巨噬细胞NLRP3炎性体激活。
6. Tacrolimus interacts with voriconazole to reduce the severity of fungal keratitis by suppressing IFN-related inflammatory responses and concomitant FK506 and voriconazole treatment suppresses fungal keratitis [O] . Jing Zhong, Lulu Peng, Bowen Wang, 2018

机译：他克莫司与伏立康唑相互作用可通过抑制IFN相关的炎症反应来降低真菌性角膜炎的严重程度同时FK506和伏立康唑治疗可抑制真菌性角膜炎
7. The effects of FK506 combined with natamycin in the treatment of experimental fungal keratitis by suppressing NLRP3 inflammasome activation [O] . Li Liang, Wei-Yun Shi 2017

机译：FK506联合纳米霉素在抑制NLRP3炎症激活治疗实验性真菌角膜炎中的影响

The effects of FK506 combined with natamycin in the treatment of experimental fungal keratitis by suppressing NLRP3 inflammasome activation:

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