SYNTHESIS AND SPECTRAL STUDIES OF NOVEL PYRIDINE, PYRIDO[2,3-D]PYRIMIDINE AND PYRIDO[2,3-D] 3,1-OXAZINE DERIVATIVES

摘要

Several novel pyridine, pyrido[2,3-d]pyrimidine and pyrido[2,3-d] 3,1-oxazine derivatives were prepared using the readily obtainable starting material 2-amino-6-aryl-4-(3,4,5-trimethoxyphenyl) pyridine-3-carbonitrile 1a,b via the reaction with one carbon donors such as phenylisothiocyanate, carbon disulphide and formic acid. The IR, 1 H-NMR and mass spectra for the new synthesized compounds were discussed.