3-(2-Chloro-pyridin-3-yl)quinazoline-2,4(1H,3H)-dione chloro-form monosolvate

摘要

The solvated title compound, C13H8ClN3O2CHCl3, is a product of a condensation reaction between 2-amino-N-(2-chloropyridin-3-yl)benzamide and phosgene. The presence of the chlorine substituent in the pyridine ring forces the latter to adopt a nearly perpendicular orientation relative to the planar quinazoline ring (r.m.s. deviation = 0.04 A? ), the two ring systems being inclined to one another by 84.28 (9). In the crystal, molecules are linked by pairs of N—HO hydrogen bonds, forming inversion dimers with an R2 2 (8) ring motif. The dimers are linked by C—HO hydrogen bonds, forming ribbons propagating along the a-axis direction. The chloroform solvent molecules are linked to the organic molecule by C—HN hydrogen bonds.