Prevalence of Helicobacter Pylori Vacuolating Cytotoxin A Gene as a Predictive Marker for Different Gastrodoudenal Diseases

摘要

Objectives: Helicobacter pylori (H. pylori) has several virulence factors such as vacA and cagA genes. Mosaicism in vacA alleles with two distinct families of vacA signal sequences (s1, s2) and two distinct families of middle region alleles (m1, m2) is reported. The aim of this study was determination of H. pylori vacA allelic types in Chaharmahal and Bakhtiyari province, Iran and their correlation with six different gastroduodenal diseases.