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Effects of Fluoride of Antarctic Krill (Euphausia superba) Meal on Accumulation and Weight of Mice

机译:南极磷虾粉中的氟化物对小鼠积累和体重的影响

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Antarctic krill (Euphausia superba) possesses rich nutritional value, large fishing capacity and potentials for processing and utilization. However, the development and utilization of Antarctic krill is impeded by its high fluorine contents. In this study, Antarctic krill meal and sodium fluoride solution (300 mg/L) were selected as the study objects to feeding mice, and the effects of fluoride on accumulation and weight gained in small intestine, blood, liver, and kidney femur of mice were investigated. The results showed that the contents of small intestine, blood, liver and kidney in the group of the mice fed with Antarctic krill and sodium fluoride remained less than 1 mg/kg, which was slightly higher than that of the blank control group (p<0.05). The fluoride contents in the femur of mice fed with Antarctic krill meal and sodium fluoride solution were ten times higher than that of the blank control group, indicating that the fluorine in Antarctic krill meal was likely different from the chemical fluorine in sodium fluoride. No signification difference on accumulation of fluoride was found in the small intestine, blood, liver and kidney of mice, but fluorine from Antarctic krill meal and sodium fluoride was obviously deposited in the femur of mice. On the other hands, the weight gained rate of mice in the sodium fluoride group was 3.22%, and that of mice in Antarctic krill meal group was 7.81%, both of that were significantly lower than that in the blank group (12.87%). The results showed that the fluorine in Antarctic krill meal inhibited the growth of mice, but its specific absorption, metabolism and transformation process in the body still needed to be further studied.
机译:南极磷虾(Euphausia superba)具有丰富的营养价值,巨大的捕捞能力以及加工和利用的潜力。然而,南极磷虾的高氟含量阻碍了其开发和利用。本研究以南极磷虾粉和氟化钠溶液(300 mg / L)为喂养小鼠的研究对象,研究了氟化物对小鼠小肠,血液,肝脏和肾脏股骨堆积和体重增加的影响。被调查了。结果表明,饲喂南极磷虾和氟化钠的小鼠组小肠,血液,肝和肾脏的含量仍低于1 mg / kg,比空白对照组略高(p < 0.05)。饲喂南极磷虾粉和氟化钠溶液的小鼠股骨中的氟含量是空白对照组的十倍,表明南极磷虾粉中的氟可能与氟化钠中的化学氟不同。在小鼠的小肠,血液,肝脏和肾脏中,氟化物的积累没有显着差异,但是南极磷虾粉中的氟和氟化钠明显沉积在小鼠的股骨中。另一方面,氟化钠组小鼠的体重增加率为3.22%,南极磷虾餐组的小鼠的体重增加率为7.81%,均明显低于空白组(12.87%)。结果表明,南极磷虾粉中的氟抑制了小鼠的生长,但其在体内的特异性吸收,代谢和转化过程仍需进一步研究。

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