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首页> 外文期刊>International Journal of Pharmacy and Pharmaceutical Sciences >SNAKE VENOM, ANTI-SNAKE VENOM & POTENTIAL OF SNAKE VENOM
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SNAKE VENOM, ANTI-SNAKE VENOM & POTENTIAL OF SNAKE VENOM

机译:蛇毒,蛇毒及蛇毒的潜力

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Many active secretions produced by animals have been employed in the development of new drugs to treat diseases such as hypertension and cancer. Snake venom toxins contributed significantly to the treatment of many medical conditions. Venomous snakes have a bad reputation and rightly so because of their often deadly bites. But what makes a snake's bite so deadly is the venom. Of the 3000 snake speci es, just over 600 are venomous. Snake venoms are made up of hundreds of different types of peptides, enzymes, and toxins. Each individual snake produces its own specific venom. There are two main types of venom viz. hemotoxins and neurotoxins. Hemotoxins target the circulatory system. They prevent clotting compounds from functioning correctly, which causes uncontrollable bleeding. Neurotoxins target the central nervous system. They stop muscles from working, which leads to suffocation. Venoms that are composed of neurotoxins are particularly deadly, as the pro teins within them are able to disrupt the channels that allow ions to flow across neuron membranes. When these communication channels are disrupted, entire body systems can crash, leading to immediate death. Medicines derived from hemotoxins are used to treat heart attacks and blood disorders. These drugs also lead to decreased incidence of stroke, kidney disease, heart failure, and diabetes. Medicines derived from neurotoxins are us ed to treat brain injuries, strokes, and diseases such as Alzheimer's and Parkinson's. Understanding the connection between the sna ke venom proteins and particular receptors could have a profound impact on the development of new treatments for diseases such as Parkinson's, Alzheimer's, and various pain disorders. An attempt has been made to review snake venom, which are anti-snake venom plants & potential of snake venoms
机译:动物产生的许多活性分泌物已被用于开发新药,以治疗高血压和癌症等疾病。蛇毒毒素对许多医学疾病的治疗有重要贡献。有毒蛇的声誉很差,由于它们经常被致命地咬伤,所以正确。但是,使蛇咬伤如此致命的是毒液。在3000种蛇中,有600种以上是有毒的。蛇毒由数百种不同类型的肽,酶和毒素组成。每条蛇都会产生自己的特定毒液。有两种主要类型的毒液。血液毒素和神经毒素。血液毒素靶向循环系统。它们会阻止凝结化合物正常运行,从而导致无法控制的出血。神经毒素靶向中枢神经系统。它们使肌肉停止工作,从而导致窒息。由神经毒素组成的毒液尤其致命,因为其中的蛋白质能够破坏允许离子流过神经元膜的通道。当这些通信渠道中断时,整个人体系统可能崩溃,导致立即死亡。衍生自hemoxinxin的药物用于治疗心脏病和血液疾病。这些药物还导致中风,肾脏疾病,心力衰竭和糖尿病的发生率降低。源自神经毒素的药物用于治疗脑损伤,中风和疾病,例如阿尔茨海默氏症和帕金森氏症。了解蛇毒蛋白与特定受体之间的联系可能会对新疗法的发展产生深远影响,例如帕金森氏症,阿尔茨海默氏症和各种疼痛性疾病。试图审查蛇毒,蛇毒是抗蛇毒植物,蛇毒的潜力

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