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A study of prevalence and association of fundus changes in pregnancy induced hypertension

机译:妊娠高血压综合征患病率和眼底变化的相关性研究

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Background: The pathological changes of pregnancy induced hypertension appear to be related to vascular endothelial dysfunction and its consequences. The retinal vascular changes generally, but not always, correlate with the severity of systemic hypertension. To find out the prevalence and association of retinal changes in pregnancy induced hypertension. Methods: A hospital based cross-sectional study was conducted where all antenatal pregnant women who fulfilled the diagnostic criteria of PIH were included in this study. Patients who had pre-existing diabetes or hypertension or renal disease or hazy media which did not permit fundus visualization were excluded from the study. Socio-demogrpahic and obstetric data was collected and all the patients were subjected to detailed clinical examination followed by fundoscopic examination. Results: Out of the total 423 patients of PIH examined, the retinal changes (hypertensive retinopathy changes) were noted in 181 (42.7%) patients. The prevalence of retinopathy changes was more among patients with imminent Eclampsia (76.5%) and eclampsia patients (50%). As the severity of the PIH increased the Odds of women developing retinopathy also increased substantially from OR: 17.6; 95% CI: 3.1-136.3 in severe PIH to OR: 253; 95% CI: 47.2-1935 in Imminent eclampsia and this association between the severity of PIH and the development of retinopathy changes was found to be statistically significant. Conclusions: Fundus examination in cases of PIH is of paramount importance in monitoring and managing cases as it co-relates with the severity of PIH.
机译:背景:妊娠高血压综合征的病理变化似乎与血管内皮功能障碍及其后果有关。视网膜血管变化通常但并非总是与全身性高血压的严重程度相关。为了查明妊娠引起的高血压的视网膜变化的发生率和相关性。方法:进行一项基于医院的横断面研究,所有符合PIH诊断标准的产前孕妇均纳入本研究。患有既往存在糖尿病,高血压,肾脏疾病或朦胧介质而无法进行眼底可视化的患者被排除在研究之外。收集社会人口和产科数据,对所有患者进行详细的临床检查,然后进行眼底镜检查。结果:在总共检查的423例PIH患者中,有181例(42.7%)出现了视网膜改变(高血压性视网膜病变改变)。即将到来的子痫患者(76.5%)和子痫患者(50%)的视网膜病变变化患病率更高。随着PIH严重程度的增加,发生视网膜病变的妇女的几率也从OR显着增加:17.6; 95%CI:3.1-136.3,严重PIH至OR:253; 95%CI:即将到来的子痫,且PIH的严重程度与视网膜病变变化的发展之间的这种关联在统计学上是显着的,其为47.2-1935。结论:PIH病例的眼底检查对于监测和管理病例至关重要,因为它与PIH的严重程度相关。

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