Cutaneous Extramedullary Plasmacytoma with Multiple Nodular Skin Lesions with an unexpected involvement of lip

摘要

Extramedullary Plasmacytoma of the skin is a rare condition especially appears with multiple skin nodules localised on chest, back, and abdomen. Here, we report a case of 47-year-old man with known extramedullary plasmacytoma who had a cervical mass initially. The patient developed cutaneous lesions on the lip, scalp, chest wall and leg in the course of the disease. Lip was an unusual involvement site in an unusual disease, cutaneous plasmacytoma. His bone marrow biopsy showed no myeloma infiltration. The histopathological diagnosis was IgGκ extramedullary plasmacytoma. Chemotherapy and radiotherapy was applied but treatment response was not good overall. Radiotherapy was effective in reducing tumor bulk and the pain associated with the lesions. However, the patient died five months later due to the systemic myeloma infiltration.