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Gastric Carcinoid Tumors: The Problems Encountered in Diagnosis and Treatment

机译:胃类癌:诊断和治疗中遇到的问题

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Gastric carcinoid tumors are rare tumors that originate from gastric enterochromaffin-like cells in the oxyntic mucosa and constitute 3.2-4% of all carcinoid tumors. Herein, outcome of a single institution experience with gastric carcinoid tumors were evaluated retrospectively. The patients with gastric carcinoid tumors were analyzed with respect to their presenting signs and symptoms, serum gastrin level, imaging studies, operative procedures and outcome of 21 patients with gastric carcinoid tumor were enrolled in this study. Sixteen patients had type 1 and 5 had type IV gastric carcinoid tumors. Endoscopic biopsy was performed in 15 patients with type I and in 2 patients with type IV. Multifocal tumor was seen in 7 patients with type I. Preoperative serum gastrin levels were high in 11 patients with type I and 3 patients with type IV gastric carcinoid tumor. In the patients with type I gastric carcinoid tumor, endoscopic mucosal resection (EMR) was performed in 6 patients with only one tumor and the tumor size less than 1 cm. In this group, 3 patients had relapse (50%). Total gastrectomy was performed in all the patients with type IV gastric carcinoid tumor. The 5-year survival of type I and IV gastric carcinoid tumors were 69.1% and 48.6%, respectively.
机译:胃类癌肿瘤是罕见的肿瘤,起源于氧化性黏膜中的胃肠嗜铬样细胞,占所有类癌的3.2-4%。在此,回顾性评估了单机构经验的胃类癌的结果。分析了胃类癌患者的体征和症状,血清胃泌素水平,影像学研究,手术程序和结果,共21例胃类癌患者。 16名1型和5型患有IV型胃类癌。内镜活检在15例I型患者和2例IV型患者中进行。 7例I型患者可见多灶性肿瘤。11例I型患者和3例IV型胃类癌患者术前血清胃泌素水平较高。在I型胃类癌患者中,对6例仅有1个肿瘤且肿瘤大小小于1 cm的患者进行了内镜黏膜切除术(EMR)。在该组中,有3例复发(50%)。所有IV型胃类癌患者均行全胃切除术。 I型和IV型胃类癌的5年生存率分别为69.1%和48.6%。

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