Eccrine angiomatous hamartoma, with verrocous hemangioma-like features: A case report

摘要

Eccrine angiomatous hamartoma (EAH) is a rare, benign cutaneous tumor. It is characterized by the proliferation of the eccrine gland elements that are closely associated with capillary proliferation. Patients usually present with a solitary nodule on the extremities that appeared at birth or during the prepubertal years. We report a rare case of EAH in a 13-year-old boy, with clinical features suggesting melanoma. Histologically, an EAH with changes resembling a verrucous hemangioma was noted. Keywords: angiomatous hamartoma, eccrine glands, verrucousIntroductionEccrine angiomatous hamartoma (EAH) is a rare benign neoplasia characterized by the proliferation of the secretory portions of the eccrine glands associated with capillary angiomatosis and proliferation in other elements, such as in the adipose tissue, hair and epidermis. ~((1)) Most cases occur at birth or in early childhood, with various forms of clinical presentation, ranging from simple angiomatous nodules to erythematous-purpuric plaques. Multiple lesions may occur, but the predominant picture is a solitary lesion.Case reportA 13-year-old boy presented with a skin lesion on the right ankle since birth. There was mild pain, but no hyperhidrosis was noted. His medical and family histories were unremarkable. Physical examination revealed a 1.5 cm raised keratotic, dark- brown plaque overlying a 3 cm light brown to bluish, ill-defined plaque on the right ankle. The lesion was excised with clinical suspicion of melanoma.The histological examination of the excised biopsy showed a hyperkeratotic verrucous surface, with numerous dilated capillaries in the papillary dermis (Fig. 1) Open in a separate windowFig. (1) Hyperkeratosis, papillomatosis, and blood vessel proliferation in the superficial dermis (H&E, ×200).