MICROWAVE ASSISTED, NICKELCOBALT FERRITE CATALYSED ONEPOT MULTICOMPONENT SYNTHESIS OF ?- ACETAMIDO KETONES

摘要

An efficient microwave assisted one pot synthesis of β-acetamido ketones from aromatic aldehydes,acetophenone, acetonitrile and acetyl chloride using nano Ni0.5Co0.5Fe2O4 ferrites as a catalyst is described,compared to mannich reaction the new method has advantage of good yield and short reaction time by simplephase separation. nano Ni0.5Co0.5Fe2O4 ferrites could be recycled several times without distinct loss of activity.