Conducting Polymer All Solid State Potentiometric Sensor for the Tramadol Assay

摘要

A new methodology was applied for the designing potentiometric membrane sensors. Anelectrochemically polymerized Poly(Pyrrole)s (PPy) film was applied as a solid contact-ion to electrontransducer on the surface of a pencil graphite electrode (PGE) to make an all-solid-state ion selectiveelectrode (CP-ASS-ISE) for the determination of Tramadol Hydrochloride. A thin layer of a PVCmembrane containing synthesized ion-pair as the active element and suitable plasticizer was thenplaced on the surface of the conducting polymer layer to prepare the sensor. The suggested sensorshowed a Nernstian response (a slope of 57.17 mV per decade) over the concentration range of -1 -1 1.010 to 1.010 mol L . The Tramadol sensor had a low detection limit of 7.410 mol L withresponse time of less than 10s in the concentrated solutions. The working pH range of the sensor was2.0-7.0. Finally, the proposed sensor used for the Tramadol assay in some pharmaceutical tablets.