A Novel Glucose Biosensor Fabricated with Electroactive Nb_0.95Ti_0.95O₄ Nano-Composite Film

摘要

A novel Nb0.95Ti0.95O4 (NTO) nanoparticle was synthesized and successfully fabricated in enzymebiosensors by integrating glucose oxidase (GOx) with a chitosan-Nb0.95Ti0.95O4 (CHITTO)nanocomposite onto an indium-tin-oxide (ITO) electrode. The results reveal that the presence of NTOcan enhance electron transfer and increase the electroactive surface area between GOx and the ITO4+ 5+ electrode. This mainly attributes to substitution of Ti by Nb to form ionization of defects improvingits electrical conductive property. The NTO-modified bioelectrode exhibits an excellent linear range,low detection limit and long shelf life. The results suggest that CHIT-NTO is a promising material forbiosensor electrode.