AbstractPlease cite this paper as: Cuevas et al. (2013) Spread of different rhinovirus B genotypes in hospitalized children in Spain. Influenza and Other Respiratory Viruses 7(5), 623–628.Human Rhinovirus (HRV) classification is an evolving process. New genotypes have been described within HRV-A and HRV-C species, but only one has been accepted related to HRV-B. From 2003 to 2010, a total of 3987 nasopharyngeal aspirate samples were taken from pediatric patients admitted to the Severo Ochoa Hospital in Madrid (Spain). After viral analysis, 949 (23·8%) tested positive to HRV. A random selection of 397 (42%) positive samples showed that 39 (9·8%) were HRV-B. The sequencing of partial VP4/VP2 coding region revealed the spread of 13 of 25 defined HRV-B serotypes and three putative new genotypes. Such results remark the high diversity of HRV-B.
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机译：摘要请引用本文为：Cuevas et al。 （2013）不同鼻病毒B基因型在西班牙住院儿童中的传播。流感和其他呼吸道病毒7（5），623-628。人类鼻病毒（HRV）分类是一个不断发展的过程。在HRV-A和HRV-C物种中已描述了新的基因型，但仅一种与HRV-B相关的基因型被接受。从2003年到2010年，共从马德里（西班牙）的Severo Ochoa医院收治的儿科患者中采集了3987份鼻咽抽吸物样品。病毒分析后，有949（23·8％）人的HRV呈阳性。随机选择397个阳性样本（42％）显示HRV-B为39个（9·8％）。 VP4 / VP2部分编码区的测序揭示了25种确定的HRV-B血清型中的13种和三种推定的新基因型的传播。这样的结果表明HRV-B的高度多样性。
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