Acidente vascular cerebral agudo: press?o arterial baixa à admiss?o implica em redu??o na expectativa de vida em 7 dias?

摘要

Normal cerebral autoregulation maintains uniform cerebral blood flow despite fluctuations in cerebral perfusion pressure between 50-150 mm Hg. This autoregulation is impaired during acute stroke resulting in a linear relationship between cerebral blood flow and cerebral perfusion pressure1. Elevated systolic blood pressure (SBP) and mean arterial pressure at presentation have been associated with poor outcomes, including early death1,2,3,4. There have been few studies that have also shown increased mortality with low SBP at baseline showing a U-shaped curve of mortality with blood pressure1,5. These studies have been largely inclusive of minor and severe strokes and there is a paucity of research done to establish an association of mortality and acute blood pressure (BP) in high-risk patients.