SYNTHESIS AND ANTIMICROBIAL STUDIES OF SOME NOVEL SCHIFF BASES

摘要

A series of Novel Schiff bases were synthesized from 4-[2-(5-Ethyl-pyridin-2-yl)-ethoxy]-phenyl amine by reacting with different aromatic aldehydes via condensation reaction. The newly Synthesized Schiff bases were confirmed by TLC, melting points, IR, 1H-NMR and mass spectra . The compound were evaluated for antibacterial activity against Bacillus subtilis gr +ve, Pseudomonas aeruginosa gr –ve , Staphylococcus aureus gr +ve, Escherichia coli–ve and antifungal activity against Aspergillus niger, Aspergillus Flavus, Curvularia, Alternaria. All the compounds shows moderate to good activity against different micro -organisms