ANTI-INFLAMMATORY, ANALGESIC AND ANTI - PYRETIC ACTIVITY OF CASSAVA LEAVES EXTRACT

摘要

Objective: The objective of this study was to evaluate the in-vivoanti-inflammatory, anti pyretic and analgesic activities and phytochemical analysis of cassava leaf extract.Material and method:The leaf extract was prepared with ethanol filter and rotary evaporated and stored in desiccator.Preliminary phytochemical screening terpernoids, tannins, flavonoids, anthraquinones, alkaloids, and cardiac glycosides and carotenoids were carried out. A different concentration (100,250,500mg/kg) of the leaf extract was evaluated for their anti-inflammary, analgesic and anti-pyretic effect using carrageenan and histamine induced oedema, acetic acid induced writhing and yeast induced pyrexia in rats respectively.Result and Conclusion: The extract at concentration100, 250,500mg/kg was able to inhibit carrageenan and histamine induced oedema,acetic acid induced writhing and yeast induced pyrexia in rats. Terpernoids, tannins, flavonoids,carotenoids were found present in the cassava leaf extract