EVALUATION OF ANTIOXIDANT AND ANTI-INFLAMMATORY PROPERTIES OF AQUEOUS EXTRACT OF WILD MUSHROOMS COLLECTED FROM HIMACHAL PRADESH

摘要

Objective: The objective of this study is to elucidate phytochemical contents, antioxidant, and anti-inflammatory activity of wild mushrooms collected from Himachal Pradesh. Methods: Quantitative analysis of phytochemical constituents was carried out using standard methods while 1,1 diphenylpicrylhydrazyl nitric oxide, hydrogen peroxide-free radical scavenging assay were used to evaluate the antioxidant properties of selected wild mushrooms. Anti-inflammatory capacity of samples was evaluated by human red blood cell membrane stabilization and albumin denaturation inhibition method. Results: The results obtained revealed that Pleurotus floridanus showed higher total phenol, flavonoid carotenoid, and ascorbic acid contents of 61.13±2.3 mg/g, 15.2±1.13 mg/g, 12.42±0.42 μg/g, 17.36±0.40 μg/g, and 14.55±0.58 mg/g. All the species showed antioxidant potential, but P. floridanus proved to be more active while Macrocybe sp. proved to be least one. Conclusion: The mushroom species analyzed have been showed to be good source of phytoconstituents, antioxidants, and also possess antiinflammatory properties, thus can be used in the management of oxidative stress-induced disease. Keywords: Wild mushrooms, Scavenging effect, Total phenol, Antioxidant, Anti-inflammatory.