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Glyphosate: cancerous or not? Perspectives from both ends of the debate

机译:草甘膦:癌与否?辩论两端的观点

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Glyphosate is an active substance that is widely used in pesticides. Glyphosate based pesticides are used in agriculture to combat weeds. They are typically applied before crops are sown and as a pre-harvest desiccating treatment, accelerating the ripening process. 5.8 kg active ingredient per hectare is recommended application dose [1]. Glyphosate, particularly its trademark Roundup, has been shown to have clear toxicity, both in laboratory tests and in epidemiological studies. Epidemiological studies have shown that glyphosate is absorbed through the skin and mucous membranes to produce neuromuscular symptoms. It increases the risk of abortion [2]. It has been related to chronic kidney diseases. Laboratory studies show several negative effects such as genotoxic effects, mutagenic effect, negative effects on estrogen-regulated gene expression, changes in the structure and functioning of cells and cytotoxicity in human cells [3].
机译:草甘膦是一种广泛用于农药的活性物质。基于草甘膦的农药在农业中用于抗除杂草。它们通常在农作物播种前和收获前进行干燥处理,以加快成熟过程。建议每公顷使用5.8千克活性成分[1]。草甘膦,特别是其商标Roundup,在实验室测试和流行病学研究中均显示出明显的毒性。流行病学研究表明,草甘膦通过皮肤和粘膜吸收,产生神经肌肉症状。它增加了流产的风险[2]。它与慢性肾脏疾病有关。实验室研究显示了几种负面作用,例如遗传毒性作用,诱变作用,对雌激素调节基因表达的负面作用,细胞结构和功能的变化以及人细胞的细胞毒性[3]。

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