Dual-Tree Complex Wavelet Transform and Twin Support Vector Machine for Pathological Brain Detection

摘要

( Aim ) Classification of brain images as pathological or healthy case is a key pre-clinical step for potential patients. Manual classification is irreproducible and unreliable. In this study, we aim to develop an automatic classification system of brain images in magnetic resonance imaging (MRI). ( Method ) Three datasets were downloaded from the Internet. Those images are of T2-weighted along axial plane with size of 256 × 256. We utilized an s -level decomposition on the basis of dual-tree complex wavelet transform (DTCWT), in order to obtain 12 s “variance and entropy (VE)” features from each subband. Afterwards, we used support vector machine (SVM) and its two variants: the generalized eigenvalue proximal SVM (GEPSVM) and the twin SVM (TSVM), as the classifiers. In all, we proposed three novel approaches: DTCWT + VE + SVM, DTCWT + VE + GEPSVM, and DTCWT + VE + TSVM. ( Results ) The results showed that our “DTCWT + VE + TSVM” obtained an average accuracy of 99.57%, which was not only better than the two other proposed methods, but also superior to 12 state-of-the-art approaches. In addition, parameter estimation showed the classification accuracy achieved the largest when the decomposition level s was assigned with a value of 1. Further, we used 100 slices from real subjects, and we found our proposed method was superior to human reports from neuroradiologists. ( Conclusions ) This proposed system is effective and feasible.