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Liquid biopsy - emergence of a new era in personalized cancer care

机译:液体活检-个性化癌症治疗新时代的出现

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The most successful treatment for cancer involves identifying druggable, biological markers for targeted therapy. In the clinical setting, surgical removal of tumors is the only procedure for identifying such targetable molecules. Shed from tumor cells, these markers are also present in circulating blood, albeit in very negligible amounts. Liquid biopsy is a procedure performed on a blood sample to look for such circulating cancer markers cells or pieces of nucleic acid from the tumor. The procedure shows promise in revolutionizing personalized cancer treatments. Here we briefly review the technique, characterization, and its utilization in clinics.
机译:癌症最成功的治疗方法包括为靶向治疗确定可药物化的生物标记。在临床环境中,手术切除肿瘤是鉴定此类可靶向分子的唯一方法。这些标志物在肿瘤细胞中脱落,尽管其量很小,但也存在于循环血液中。液体活检是对血液样本进行的程序,以从肿瘤中寻找这种循环的癌症标志物细胞或核酸片段。该程序在革新个性化癌症治疗方面显示出希望。在这里,我们简要回顾一下该技术,特征及其在临床中的应用。

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