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A Case of Porokeratosis of Hands and Feet Turning into a Squamous Cell Carcinoma

机译:手脚角化病成鳞状细胞癌一例

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Porokeratosis is comprised of heterogeneous group of diseases that inherited as autosomal dominant pattern. It is a disorder of keratinization characterized by one or more atrophic macules or patches, each surrounded by a distinctive hyperkeratotic, ridge-like border called a cornoid lamella. Multiple clinical variants of porokeratosis exist, some of them have genetic inheritance while others are acquired and malignant transformation occurs in a minority of cases. In Iraq, the inherited commonly described entities of porokeratosis are rarely seen, but every now and then localized forms like porokeratosis of the scrotum and other parts of the body were seen. In addition solar facial porokeratosis is an acquired disease not uncommonly seen in young females which disappear over time. The aim of the present report is to record an unusual case of localised porokeratosis of both hands and feet with multiple squamous cell carcinomas with negative family history.
机译:猪角化病是由常染色体显性遗传的异质性疾病组成。它是一种角化病,其特征是一个或多个萎缩性黄斑或斑块,每个斑块或斑块周围都有独特的角化性角化层,称为角质层。存在多种眼角膜异位症的临床变体,其中一些具有遗传遗传,而其他则获得,并且在少数情况下会发生恶性转化。在伊拉克,很少见到遗传的,通常描述为角膜曲霉病的实体,但是时不时地看到诸如阴囊和身体其他部位的角膜曲霉病的局部形态。另外,日光性面部角膜角化病是一种在年轻女性中不常见的后天性疾病,随着时间的推移会消失。本报告的目的是记录家族性阴性的多发鳞状细胞癌的手脚局限性角化病的罕见病例。

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