Colon Adenocarcinoma Associated with Synchronous Extramural Gastrointestinal Stromal Tumor (GIST) of the Ileum

摘要

Patient: Female, 68 Final Diagnosis: Gastrointestinal stromal tumour and colon adenocarcinoma Symptoms: Fatigue Medication: — Clinical Procedure: Right Hemicolectomy and enterectomy Specialty: Surgery Objective: Rare disease Background: GISTs are mesenchymal tumors representing approximately 1% of all gastrointestinal neoplasia. Their concurrence with colorectal cancers is rare. Case Report: We present a case of coexistence of colon adenocarcinoma and GIST of the ileum in a 68-year-old white woman. Conclusions: The coexistence of mesenchymal and epithelial neoplasia is very challenging; further research is needed to clarify the role of oncogenic mutations and signalling pathways in carcinogenesis of neoplasia of various histiogenic origins.