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Gross and Histomorphological Studies of Femoral Head Resurfacing in Dog | Science Publications

机译:狗股骨头表面置换的总体和组织形态学研究科学出版物

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> The foetal skull bone as a biological graft was investigated. This study was conducted on Fifteen adult mixed - breed normal dogs 12 to 24 months with weighing 21.4=3.6 Kg .Dogs were randomly divided into 3 groups of 5 animals each. The foetal skull bone of 45 days old was collected from one pregnant bitch via cesarean method. The right femoral head cartilage was removed completely in all dogs of 3 groups.. Group I acted as control one, whereas in II group, resurfacing was done by using foetal skull bone which was fixed by using 0.8 mm cerclage wire in criss-cross fashion, but in III group, it was done similar to II group and the hip joint additionally was fixed by using 2 mm steinmenn pin.The clinical observations was made accordingly for 60 days in all groups. The gross changes of femoral head in group I & II were quite smooth and slippy, but in III group were uneven and rough due to secondary changes and ankylosis, but on micropscopic interpertation there was a remarkable compatibility of the graft with femoral head.The reconstruction of articular cartilage was faster in group II and even group III animals than group I animals. There was single row of chondrocyte in scatter area of samples in group . The complete and uniform hyaline cartilage in group II and fibro - cartilage and mixture of connective tissues in group III animals were observed. The results indicated that the foetal skull bone due to its pleuripotent calvarium easily can orient itself into the chondrocytes and cartilagenous tissues in articular surface of the hip joint, if there is suitable enviroment before complete ossification,so that normal joint motion could expect.
机译: >对胎儿颅骨作为生物移植物进行了研究。这项研究是对15只成年混合品种的正常狗(12至24个月)进行的,它们的体重为21.4 = 3.6 Kg。狗随机分为3组,每组5只动物。通过剖宫产术从一个怀孕的母犬中收集了45天大的胎儿颅骨。 3组中的所有犬均完全清除了右股骨头软骨。.I组作为对照组,而II组中,使用胎头颅骨进行重铺,该颅骨通过0.8 mm环扎线以十字交叉方式固定但在III组中,其操作与II组相似,并另外使用2 mm的steinmenn销钉固定了髋关节。所有组均进行了60天的临床观察。 I&II组股骨头的总体变化相当平滑和滑溜,但III组由于继发性变化和强直性反应而凹凸不平且粗糙,但在显微镜下观察到移植物与股骨头具有显着的相容性。 II组甚至III组动物的关节软骨生长速度快于I组动物。组散布区域的软骨细胞为单排。在第二组中观察到完整和均匀的透明软骨,在第三组动物中观察到纤维软骨和结缔组织的混合物。结果表明,由于颅骨具有多能性颅骨,如果在完全骨化之前有合适的环境,则容易将其定向到髋关节关节表面的软骨细胞和软骨组织中,从而可以期待关节的正常运动。

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