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The Effect of a Femoral Fracture Sustained before Skeletal Maturity on Bone Mineral Density: A Long-Term Follow-Up Study

机译:骨骼成熟前保持股骨骨折对骨矿物质密度的影响:一项长期随访研究

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Background and Purpose.The possible effect of pediatric femoral fractures on the bone mineral density (BMD) is largely unknown. We conducted a study to investigate BMD in adults who had sustained a femoral shaft fracture in childhood treated with skeletal traction.Materials and Methods.Forty-four adults, who had had a femoral fracture before skeletal maturity, were reexamined on average 21 (range 11.4) years after treatment. Our follow-up study included a questionnaire, a clinical examination, length and angle measurements of the lower extremities from follow-up radiographs, and a DEXA examination with regional BMD values obtained for both legs separately.Results.At follow-up femoral varus-valgus(P=0.001)and ante-/recurvatum(P=0.001)angles were slightly larger in the injured lower-limb compared to the contralateral limb. The mean BMD of the entire injured lower-limb was lower than that of the noninjured (1.323 g/cm2versus 1.346 g/cm2,P=0.003). Duration of traction was the only factor in multiple linear regression analysis that was positively correlated with the BMD discrepancy between the injured and noninjured lower-limb explaining about 17% of its variation.Conclusion.The effect of a femoral fracture sustained during growth is small even in patients treated with traction.
机译:背景与目的小儿股骨骨折对骨矿物质密度(BMD)的可能影响尚不清楚。我们进行了一项研究,以调查接受骨骼牵引治疗的儿童时期发生股骨干骨折的成年人的骨密度(BMD)。材料和方法。四十四名成年人在骨骼成熟前发生股骨骨折,平均接受21次检查(范围11.4) )治疗后的数年。我们的随访研究包括问卷调查,临床检查,从随访X线照片检查的下肢长度和角度,以及分别获得双腿的区域BMD值的DEXA检查。与对侧肢体相比,受伤下肢的外翻角(P = 0.001)和前/后弯角(P = 0.001)稍大。整个受伤下肢的平均骨密度低于未受伤的骨密度(1.323μg/ cm2对1.346μg/ cm2,P = 0.003)。牵引的持续时间是多重线性回归分析中与受伤和未受伤的下肢之间的BMD差异呈正相关的唯一因素,可以解释其变化的17%。结论。在生长过程中持续发生的股骨骨折的影响很小在接受牵引治疗的患者中。

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