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A Case of Streptococcus anginosus Brain Abscess Caused by Contiguous Spread from Sinusitis in an Immunocompetent Patient

机译:连续性鼻窦炎传播引起免疫性疾病患者的链球菌性心绞痛脑脓肿一例

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Brain abscesses are infections of the brain parenchyma that can arise from either contiguous spread from local infection or by hematogenous spread from a distant site. Streptococcus anginosus of the Streptococcus anginosus group (SAG) is a commensal microbe of the mucosae of the oral cavity, gastrointestinal tract, and urogenital tract. We present a case of mono-microbial brain abscess caused by contiguous spread from relatively asymptomatic sinusitis that initially presented as a subdural hemorrhage on computed tomography. A 70-year-old male presented, obtunded, with a Glasgow Coma Score?of eight. The patient seized on arrival. A computed tomography scan was read as a subdural hemorrhage, and magnetic resonance imaging showed a heterogeneous area at the anterior tip of the left frontal lobe?interpreted as a frontoparietal abscess, along with pansinusitis. Craniotomy revealed a loculated abscess. Culture grew only Streptococcus anginosus. The patient did well postoperatively, was extubated by day five with rapidly improving neurological function, and was discharged to inpatient rehab by hospital-day eight for the continuation of intravenous antibiotics. This case represents a frontal lobe abscess caused by the contiguous spread of Streptococcus anginosus from a frontal sinus infection. This is a relatively rare presentation of SAG infection in an immunocompetent patient. The case outlines the importance of imaging modality choice in the various stages of brain abscess formation, and the necessity of maintaining an index of suspicion for brain abscess in patients with few traditional risk factors and little to no history on presentation.
机译:脑脓肿是脑实质的感染,可能是由于局部感染引起的连续性扩散,也可能是由于远处的血源性扩散引起的。链球菌(Angularsus)组(SAG)的链球菌是口腔,胃肠道和泌尿生殖道黏膜的共生微生物。我们提出了一例由相对无症状的鼻窦炎连续传播引起的单微生物脑脓肿的病例,该病最初表现为计算机断层摄影术中的硬脑膜下出血。一名70岁的男性表现不佳,格拉斯哥昏迷评分为8分。病人在抵达时被查获。电脑断层扫描被认为是硬膜下出血,磁共振成像显示左额叶前尖端的异质性区域,被解释为额腹前部脓肿以及全神经炎。开颅手术发现有脓肿。文化只生长链球菌。该患者术后状况良好,在第5天拔管并迅速改善神经功能,并在第8天住院恢复出院以继续静脉使用抗生素。该病例代表额叶脓肿是由额窦感染引起的链球菌性心绞痛的连续传播引起的。这是具有免疫功能的患者中SAG感染的一种相对罕见的表现。该病例概述了在脑脓肿形成的各个阶段进行影像学方式选择的重要性,以及在传统危险因素很少且几乎没有病史的患者中维持脑脓肿可疑指标的必要性。

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