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Acute Phase Response in Animals: A Review

机译:动物急性期反应:综述

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摘要

Theacutephaseresponseisacomplexsystemicearly-defensesystemactivatedbytrauma,infection,stress,neoplasia,andinflammation.Althoughnonspecific,itservesasacoreoftheinnateimmuneresponseinvolvingphysicalandmolecularbarriersandresponsesthatservetopreventinfection,clearpotentialpathogens,initiateinflammatoryprocesses,andcontributetoresolutionandthehealingprocess.Acutephaseproteins,anintegralpartoftheacutephaseresponse,havebeenafocusofmanyapplicationsinhumandiagnosticmedicineandrecentlyhavebeenidentifiedincommonanimalspecies.Potentialapplicationstodiagnosis,prognosis,assessmentofanimalhealth,andlaboratoryanimalwelfarearereadilyapparent.
机译:Theacutephaseresponseisacomplexsystemicearly-defensesystemactivatedbytrauma,感染,应激,瘤形成,andinflammation.Althoughnonspecific,itservesasacoreoftheinnateimmuneresponseinvolvingphysicalandmolecularbarriersandresponsesthatservetopreventinfection,clearpotentialpathogens,initiateinflammatoryprocesses,andcontributetoresolutionandthehealingprocess.Acutephaseproteins,anintegralpartoftheacutephaseresponse,havebeenafocusofmanyapplicationsinhumandiagnosticmedicineandrecentlyhavebeenidentifiedincommonanimalspecies.Potentialapplicationstodiagnosis,预后,assessmentofanimalhealth,andlaboratoryanimalwelfarearereadilyapparent。

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