Cyclosporine C2 Monitoring for the Treatment of Frequently Relapsing Nephrotic Syndrome in Children: A Multicenter Randomized Phase II Trial

Hidefumi Nakamura; Hiroshi Hataya; Kandai Nozu; Kazumoto Iijima; Kenji Ishikura; Koichi Kamei; Koichi Nakanishi; Mari Saito Oba; Masataka Honda; Mayumi Sako; Michio Nagata; Nahoko Yata; Norishige Yoshikawa; Ryojiro Tanaka; Shuichi Ito; Yasuo Ohashi; Yoko Ohwada

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Cyclosporine C2 Monitoring for the Treatment of Frequently Relapsing Nephrotic Syndrome in Children: A Multicenter Randomized Phase II Trial

机译：环孢素C2监测治疗儿童频繁复发的肾病综合征：一项多中心随机II期试验。

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Background and objectives An open-label, multicenter, randomized phase II trial was conducted from July 1, 2005 to March 29, 2011 to compare two protocols for treating children with frequently relapsing nephrotic syndrome using microemulsified cyclosporine.

机译：背景与目标从2005年7月1日至2011年3月29日，进行了一项开放性，多中心，随机的II期临床试验，比较了两种使用微乳化环孢菌素治疗患有频繁复发性肾病综合征的儿童的方案。

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《Clinical journal of the American Society of Nephrology: CJASN》 |2014年第2期|共页
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Hidefumi Nakamura; Hiroshi Hataya; Kandai Nozu; Kazumoto Iijima; Kenji Ishikura; Koichi Kamei; Koichi Nakanishi; Mari Saito Oba; Masataka Honda; Mayumi Sako; Michio Nagata; Nahoko Yata; Norishige Yoshikawa; Ryojiro Tanaka; Shuichi Ito; Yasuo Ohashi; Yoko Ohwada;
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中图分类泌尿科学（泌尿生殖系疾病）;
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1. Cyclosporine C2 monitoring for the treatment of frequently relapsing nephrotic syndrome in children: A multicenter randomized phase II trial [J] . IijimaK., SakoM., ObaM.S., Clinical journal of the American Society of Nephrology: CJASN . 2014,第2期

机译：环孢素C2监测对儿童频繁复发性肾病综合征的治疗：一项多中心随机II期试验
2. Study protocol: mycophenolate mofetil as maintenance therapy after rituximab treatment for childhood-onset, complicated, frequently-relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: a multicenter double-blind, randomized, placebo-controlled trial (JSKDC07) [J] . Tomoko Horinouchi, Mayumi Sako, Koichi Nakanishi, BMC Nephrology . 2018,第1期

机译：研究方案：利妥昔单抗治疗后的霉酚酸酯作为儿童期发作的，复杂的，经常复发的肾病综合征或类固醇依赖性肾病综合征的维持治疗：一项多中心，双盲，随机，安慰剂对照试验（JSKDC07）
3. Study protocol: multicenter double-blind, randomized, placebo-controlled trial of rituximab for the treatment of childhood-onset early-stage uncomplicated frequently relapsing or steroid-dependent nephrotic syndrome (JSKDC10 trial) [J] . China Nagano, Mayumi Sako, Koichi Kamei, BMC Nephrology . 2019,第1期

机译：研究方案：利妥昔单抗的多中心双盲，随机，安慰剂对照试验，用于治疗儿童期早期早期并发的频繁复发或类固醇依赖性肾病综合征（JSKDC10试验）
4. Curosurf versus survanta in the treatment of neonatal respiratory distress syndrome in preterm infants: results from a randomized, multicenter masked comparison trial. [C] . Acta pharmacologica sinica . 2002

机译：Curosurf vs survanta在早产儿新生儿呼吸窘迫综合征的治疗中：一项来自随机，多中心，掩盖比较试验的结果。
5. Comparison of Performance of Two Clinical Scales to Assess the Post-Thrombotic Syndrome: Secondary Analysis of a Multicenter Randomized Trial of Pharmacomechanical Catheter-Directed Thrombolysis for Deep Vein Thrombosis [D] . Lee, Angela Young-Ju. 2020

机译：两种临床尺度的性能比较评估后血栓形成后综合征：对深静脉血栓形成的药物机械导管导向溶栓的多中心随机试验的二次分析
6. Study protocol: mycophenolate mofetil as maintenance therapy after rituximab treatment for childhood-onset complicated frequently-relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: a multicenter double-blind randomized placebo-controlled trial (JSKDC07) [O] . Tomoko Horinouchi, Mayumi Sako, Koichi Nakanishi, 2018

机译：研究方案：利妥昔单抗治疗后的霉酚酸酯作为儿童期发作的复杂的经常复发的肾病综合征或类固醇依赖性肾病综合征的维持疗法：一项多中心双盲随机安慰剂对照试验（JSKDC07）
7. Significance of combined cyclosporine−prednisolone therapy and cyclosporine blood concentration monitoring for idiopathic membranous nephropathy with steroid-resistant nephrotic syndrome: a randomized controlled multicenter trial [O] . Takao Saito, null null, Masayuki Iwano, 2013

机译：环孢素-泼尼松龙联合治疗和环孢素血药浓度监测对特发性膜性肾病合并类固醇抵抗性肾病的意义：一项随机对照多中心试验

Cyclosporine C2 Monitoring for the Treatment of Frequently Relapsing Nephrotic Syndrome in Children: A Multicenter Randomized Phase II Trial

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