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首页> 外文期刊>Clinical and Translational Medicine >Erratum to: Integrated EpCAM-independent subtraction enrichment and iFISH strategies to detect and classify disseminated and circulating tumors cells
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Erratum to: Integrated EpCAM-independent subtraction enrichment and iFISH strategies to detect and classify disseminated and circulating tumors cells

机译:勘误到:集成的独立于EpCAM的减法富集和iFISH策略,以检测和分类已扩散和正在循环的肿瘤细胞

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Erratum to: Clin Trans Med (2015) 4:38 DOI 10.1186/s40169-015-0081-2 The abstract of the original article in Clinical and Translational Medicine [ 1 ] contained an error. In the first sentence the words “Anti-epithelial cell adhesion” were incorrectly added. Find the incorrect and corrected sentences below. Incorrect sentence: Application of tumor cell surface adhesion molecule Anti-epithelial cell adhesion molecule (EpCAM)-dependent antibody capture, and intracellular cytokeratins (CKs)-dependent immunostaining strategies to detect disseminated or circulating tumor cells (DTCs or CTCs), is limited by highly heterogeneous and dynamic expression or absence of EpCAM and/or CKs in CTCs and DTCs, particularly in their capturing and identifying CTCs/DTCs shed from diverse types of solid tumor, thus being biased and restricted to the only both EpCAM and CK positive cancer cells. Corrected sentence: Application of tumor cell surface adhesion molecule EpCAM-dependent antibody capture, and intracellular cytokeratins (CKs)-dependent immunostaining strategies to detect disseminated or circulating tumor cells (DTCs or CTCs), is limited by highly heterogeneous and dynamic expression or absence of EpCAM and/or CKs in CTCs and DTCs, particularly in their capturing and identifying CTCs/DTCs shed from diverse types of solid tumor, thus being biased and restricted to the only both EpCAM and CK positive cancer cells. The abstract in the original article has been corrected.
机译:勘误表:Clin Trans Med(2015)4:38 DOI 10.1186 / s40169-015-0081-2《临床和转化医学》 [1]中原始文章的摘要包含一个错误。在第一句中,错误地添加了“抗上皮细胞粘附”一词。在下面找到不正确和更正的句子。错误的句子:肿瘤细胞表面粘附分子的应用抗上皮细胞粘附分子(EpCAM)依赖的抗体捕获和细胞内角蛋白(CKs)依赖的免疫染色策略来检测弥散或循环中的肿瘤细胞(DTC或CTC)受以下限制在CTC和DTC中高度异质和动态表达或不存在EpCAM和/或CK,特别是在捕获和鉴定源自多种类型实体瘤的CTC / DTC时,因此被偏爱并仅限于EpCAM和CK阳性癌细胞。正确的句子:肿瘤细胞表面粘附分子依赖EpCAM的抗体捕获和依赖细胞内细胞角蛋白(CKs)的免疫染色策略来检测已扩散或循环的肿瘤细胞(DTC或CTC)的应用受到高度异质和动态表达或缺乏CTC和DTC中的EpCAM和/或CK,特别是在捕获和鉴定来自各种类型实体瘤的CTC / DTC中,因此受到偏见并仅限于EpCAM和CK阳性癌细胞。原始文章中的摘要已得到纠正。

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