Optimization and in vitro antiproliferation of Curcuma wenyujin ’s active extracts by ultrasonication and response surface methodology

摘要

Background Curcuma wenyujin, a member of the genus Curcuma, has been widely prescribed for anti-cancer therapy. Multiple response surface optimization has attracted a great attention, while, the research about optimizing three or more responses employing response surface methodology (RSM) was very few.