A 67-year-old man is discharged from a peripheral hospital after a short stay in orthopedics for mild thoracic trauma. He is readmitted to the ED 2 hours later for severe dyspnea. His medical history includes acute myocardial ischemia and paroxysmal atrial fibrillation.The patient is admitted to the ICU where he is first supported with CPAP and then with mechanical ventilation. Despite maximal ventilator support and pronation, gas exchanges and lung mechanics progressively deteriorate; he is addressed to our ICU for rescue venovenous extracorporeal membrane oxygenation (ECMO). At arrival, CT scan shows bilateral honeycombing pattern with diffuse thickening of interlobular septa (Fig 1
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