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Paediatric intracranial meningiomas: eight-year experience with 32 cases

机译:小儿颅内脑膜瘤:八年经验32例

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BackgroundThe information about paediatric meningiomas is poor. The purpose of this study was to review the clinical characteristic, treatment considerations and prognosis of paediatric meningiomas. MethodsWe retrospectively reviewed a series of 32 paediatric patients with meningiomas who received surgical resection at the Affiliated Hospital of Qingdao University between January 2002 and December 2010. ResultsThe study group included 17 boys and 15 girls (range: 2–18?years, mean: 13.7?years). Thirteen patients were in the first decade of life and 19 patients were in the second decade. The most common symptoms were headache (33.3%) and epilepsy (25%), followed by cranial nerve dysfunction: distortion of commissure, vision disorder, acoasma and unconsciousness. The size of lesions was ranged 35–65?mm (mean 42.3?mm). Of these 32 patients, 16 were revealed WHO class I meningiomas, 5 were WHO class II, and 11 manifested WHO class III. Nine of 32 patients met the criteria that had tumor recurrence within follow-up. ConclusionsPaediatric meningiomas usually have larger size, higher pathologic grade and unusual location. The influential factors for recurrence include lesion location, histological features and extent of removal. Complete tumor resection is the best choice to prevent recurrence and improve the prognosis.
机译:背景关于小儿脑膜瘤的信息很差。这项研究的目的是审查儿童脑膜瘤的临床特征,治疗注意事项和预后。方法我们回顾性回顾了2002年1月至2010年12月在青岛大学附属医院接受外科手术切除的32例小儿脑膜瘤患者。结果研究组包括17名男孩和15名女孩(范围:2-18岁,平均:13.7岁)。 ?年份)。生命的第一个十年有13名患者,第二个十年有19名患者。最常见的症状是头痛(33.3%)和癫痫症(25%),其次是颅神经功能障碍:连合畸形,视力障碍,暗哑和意识丧失。病变范围为35-65?mm(平均42.3?mm)。在这32例患者中,有16例被发现为WHO I类脑膜瘤,5例为WHO II类,11例为WHO III类。 32例患者中有9例符合随访中肿瘤复发的标准。结论小儿脑膜瘤通常较大,病理分级较高,且位置异常。复发的影响因素包括病变部位,组织学特征和切除范围。完全切除肿瘤是预防复发和改善预后的最佳选择。

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