Oral Low-dose Theophylline on Top of Inhaled Fluticasone-Salmeterol Does Not Reduce Exacerbations in Patients With Severe COPD: A Pilot Clinical Trial

Borja G. Cosío; Hanaa Shafiek; Amanda Iglesias; Aina Yanez; Rocío Córdova; Alexandre Palou; Robert Rodriguez-Roisin; Germán Peces-Barba; Sergi Pascual; Joaquim Gea; Oriol Sibila; Peter J. Barnes; Alvar Agusti

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Oral Low-dose Theophylline on Top of Inhaled Fluticasone-Salmeterol Does Not Reduce Exacerbations in Patients With Severe COPD: A Pilot Clinical Trial

机译：吸入轻度氟替卡松-沙美特罗上方口服小剂量茶碱不能减轻严重COPD患者的病情恶化：一项临床试验

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摘要

COPD is characterized by an abnormal inflammatory response to inhaled particles and gases, mostly tobacco smoking, that flares up during exacerbations of the disease.

机译：COPD的特征是对吸入的颗粒和气体（主要是吸烟）的异常炎症反应，在疾病加重期间会突然发作。

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来源
《Chest》 |2016年第1期|共8页
作者
Borja G. Cosío; Hanaa Shafiek; Amanda Iglesias; Aina Yanez; Rocío Córdova; Alexandre Palou; Robert Rodriguez-Roisin; Germán Peces-Barba; Sergi Pascual; Joaquim Gea; Oriol Sibila; Peter J. Barnes; Alvar Agusti;
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中图分类呼吸系及胸部疾病;
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1. Oral Low-dose Theophylline on Top of Inhaled Fluticasone-Salmeterol Does Not Reduce Exacerbations in Patients With Severe COPD A Pilot Clinical Trial [J] . Cosio Borja G., Shafiek Hanaa, Iglesias Amanda, Chest: The Journal of Circulation, Respiration and Related Systems . 2016,第1期

机译：重度COPD患者口服氟替卡松-沙美特罗口服低剂量茶碱不能减轻病情恶化的临床试验
2. Oral Low-dose Theophylline on Top of Inhaled Fluticasone-Salmeterol Does Not Reduce Exacerbations in Patients With Severe COPD: A Pilot Clinical Trial [J] . Borja G. Cosío, Hanaa Shafiek, Amanda Iglesias, Chest . 2016,第1期

机译：吸入轻度氟替卡松-沙美特罗上方口服小剂量茶碱不能减轻严重COPD患者的病情恶化：一项临床试验
3. Effect of Theophylline as Adjunct to Inhaled Corticosteroids on Exacerbations in Patients With COPDA Randomized Clinical Trial [J] . Graham?Devereux, Seonaidh?Cotton, Shona?Fielding, JAMA: the Journal of the American Medical Association . 2018,第15期

机译：茶碱作为吸入皮质类固醇对COPDA随机临床试验患者加剧的辅助性辅助性的影响
4. Piloting the European Unified Patient Identity Management (EUPID) Concept to Facilitate Secondary Use ofNeuroblastoma Data from Clinical Trials and Biobanking [C] . Hubert EBNER, Dieter HAYN, Markus FALGENHAUER, eHealth Conference . 2016

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5. Comparing Oral and Intravenous Acetaminophen for Reducing Postoperative Opioid Requirements in Bariatric Surgical Patients [D] . Cummens, Matt. 2019

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6. Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial [O] . Graham Devereux, Seonaidh Cotton, Peter Barnes, 2015

机译：使用小剂量口服茶碱作为吸入性糖皮质激素的辅助剂预防慢性阻塞性肺疾病的恶化：一项随机对照试验的研究方案
7. Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial [O] . Graham Devereux, Seonaidh Cotton, Peter Barnes, 2015

机译：使用小剂量口服茶碱作为吸入性糖皮质激素的辅助药物预防慢性阻塞性肺疾病的恶化：一项随机对照试验的研究方案

Oral Low-dose Theophylline on Top of Inhaled Fluticasone-Salmeterol Does Not Reduce Exacerbations in Patients With Severe COPD: A Pilot Clinical Trial

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