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首页> 外文期刊>Canadian Journal of Veterinary Research >Utilisation du mélange lidocaïne-butorphanol en anesthésie épidurale caudale chez la jument.
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Utilisation du mélange lidocaïne-butorphanol en anesthésie épidurale caudale chez la jument.

机译:利多卡因-布托啡诺混合物在母马尾硬膜外麻醉中的应用。

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摘要

Loss of rear motor control is the main limiting factor in the use of caudal epidural anesthesia in the horse. In man and laboratory animals, a small dose of an opiate combined with a local anesthetic enhances analgesia without impairing motor function. Thus, the amount of local anesthetic administered may be reduced. Butorphanol is an opiate widely used in horses. It has a good margin of safety and few cardiorespiratory effects. The effects of lidocaine (0.25 mg/kg) and lidocaine-butorphanol (0.25 mg/kg, and 0.04 mg/kg, respectively) were compared in 2 groups of 5 healthy unsedated mares. Horses in each group received either lidocaine or lidocaine-butorphanol in saline solution for a total volume of 0.0165 mg/kg. Epidural injection was performed at the first coccygeal interspace. Each mare was used only once. Cutaneous analgesia was assessed by a response to a pin prick; and visceral analgesia was assessed by response to a noxious stimulus applied to the urethra. Heart rate, respiratory rate, and arterial blood pressure were also measured. Analysis of the results showed an increase in duration of both cutaneous and visceral analgesia in the mares given lidocaine-butorphanol. Cutaneous analgesia increased from 36 +/- 13 to 150 +/- 21 min and visceral analgesia increased from 22 +/- 10 to 162 +/- 16 min. A cranial extension of the cutaneous analgesia was also observed. Cardiorespiratory depression or signs of excitation were not observed. However, these mares demonstrated peculiar walking in the hind limbs, not associated with signs of ataxia or hyperkinesia.
机译:后方运动控制的丧失是在马中使用尾硬膜外麻醉的主要限制因素。在人和实验动物中,小剂量的鸦片剂与局部麻醉剂结合可增强镇痛效果,而不会损害运动功能。因此,可以减少局部麻醉剂的施用量。布托啡诺是一种广泛用于马匹的鸦片剂。它具有良好的安全性和很少的心肺功能。在2组5只健康的未镇静母马中比较了利多卡因(0.25 mg / kg)和利多卡因-丁烷醇(分别为0.25 mg / kg和0.04 mg / kg)的作用。每组中的马接受盐溶液中的利多卡因或利多卡因-丁啡诺,总体积为0.0165 mg / kg。在第一个尾椎间隙进行硬膜外注射。每个母马只使用一次。皮肤镇痛通过对针刺的反应来评估。通过对尿道施加有害刺激来评估内脏镇痛效果。还测量了心率,呼吸率和动脉血压。结果分析表明,给予利多卡因-丁啡诺的母马皮肤和内脏镇痛持续时间增加。皮肤镇痛从36 +/- 13分钟增加到150 +/- 21分钟,内脏镇痛从22 +/- 10分钟增加到162 +/- 16分钟。还观察到了皮肤镇痛的颅骨扩展。未观察到心脏呼吸抑制或兴奋迹象。但是,这些母马在后肢表现出奇特的行走,与共济失调或运动亢进的迹象无关。

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