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Life with Oxidative Stress

机译:氧化应激的生活

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Incomplete oxygen reduction gives rise to reactive oxygen species (ROS). For a long time they have been considered unwelcome companions of aerobic metabolism. Organisms using oxygen developed several systems of ROS scavenging with enzymatic and non enzymatic antioxidants, which allow them control the cellular level of oxygen derived from free radicals. It is well established nowadays that ROS are not necessarily negative byproducts, but they also play an important role in cellular mechanisms. They are involved in many regular cellular processes in all aerobic organisms. When the antioxidant system is overcome and the balance between ROS production and scavenging is disrupted, oxidative stress occurs. It has been reported that oxidative stress may be linked to some human diseases and is also involved in biotic and abiotic stress response in plants.
机译:不完全的氧气还原会产生活性氧(ROS)。长期以来,它们一直被认为是有氧代谢的不受欢迎伴侣。使用氧气的生物体开发了几种用酶促和非酶促抗氧化剂清除ROS的系统,这使它们能够控制自由基产生的氧的细胞水平。如今,众所周知,ROS不一定是阴性副产物,但它们在细胞机制中也起着重要作用。他们参与了所有有氧生物的许多常规细胞过程。当抗氧化剂系统被克服并且ROS产生和清除之间的平衡被破坏时,发生氧化应激。据报道,氧化胁迫可能与某些人类疾病有关,并且还参与植物的生物和非生物胁迫反应。

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