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BioMiner: Paving the Way for Personalized Medicine

机译:BioMiner:为个性化医学铺平道路

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Personalized medicine is promising a revolution for medicine and human biology in the 21st century. The scientific foundation for this revolution is accomplished by analyzing biological high-throughput data sets from genomics, transcriptomics, proteomics, and metabolomics. Currently, access to these data has been limited to either rather simple Web-based tools, which do not grant much insight or analysis by trained specialists, without firsthand involvement of the physician. Here, we present the novel Web-based tool “BioMiner,” which was developed within the scope of an international and interdisciplinary project (SYSTHER?) and gives access to a variety of high-throughput data sets. It provides the user with convenient tools to analyze complex cross-omics data sets and grants enhanced visualization abilities. BioMiner incorporates transcriptomic and cross-omics high-throughput data sets, with a focus on cancer. A public instance of BioMiner along with the database is available at http://systherDB.microdiscovery.de/, login and password: “systher”; a tutorial detailing the usage of BioMiner can be found in the Supplementary File.
机译:个性化医学有望在21世纪掀起一场医学和人类生物学的革命。这项革命的科学基础是通过分析来自基因组学,转录组学,蛋白质组学和代谢组学的生物高通量数据集来实现的。当前,对这些数据的访问仅限于相当简单的基于Web的工具,如果没有医生的直接参与,这些工具不会给予受过训练的专家太多的见识或分析。在这里,我们介绍了新颖的基于Web的工具“ BioMiner”,该工具是在国际跨学科项目(SYSTHER?)的范围内开发的,并且可以访问各种高通量数据集。它为用户提供了方便的工具来分析复杂的跨组学数据集并授予增强的可视化功能。 BioMiner整合了转录组学和跨组学高通量数据集,重点关注癌症。可在http://systherDB.microdiscovery.de/上获得BioMiner的公共实例以及数据库,登录名和密码:“ systher”;可以在补充文件中找到详细介绍BioMiner用法的教程。

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