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Effectiveness of medical treatment in overcoming the ureteral double-J stent related symptoms

机译:药物治疗克服输尿管双J支架相关症状的有效性

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Background: We investigated whether the frequency of lower urinary tract symptoms (LUTS) increased in patients in whom double-J stents were applied. We also evaluated several medical therapy protocols to treat symptoms related with ureteral stents. Materials and Methods: A total of 108 patients, in whom unilateral double-j stent was applied during ureteral stone treatment, were included. Before the double-J stent was applied, all patients completed storage components of the “International Prostate Symptom Score” (IPSSs), quality of life components of the IPSS (IPSS-QOL) and “Overactive Bladder Questionnaire” (OABq) forms and scores were calculated. After the procedure, cases were randomized into 5 groups, an antiinflammatory was given to Group 1, spasmolytic to Group 2, anticholinergic to Group 3 and α-blocker to Group 4. No additional drug was given to Group 5 as this control group. During the fourth week of the procedure, IPSSs, IPSS-QOL and OABq forms were again completed and scores were compared with the previous ones. Results: When all the cases were evaluated, the IPSSs, IPSS-QOL and OABq scores of patients in whom the double-J stent was applied were statistically significantly higher the procedure. Compared to the control group, the cases where the double-J stent was applied showed a higher IPSSs, IPSS-QOL and OABq scores and none of the medical therapies could prevent this increase. Interpretation: The frequency of LUTS increased in cases where the ureteral stent was applied and discomfort continued as long as the stent stayed in the body.
机译:背景:我们调查了在使用双J支架的患者中下尿路症状(LUTS)的频率是否增加。我们还评估了几种治疗输尿管支架相关症状的药物治疗方案。材料与方法:总共包括108例在输尿管结石治疗期间应用了单侧double-j支架的患者。在应用双J支架之前,所有患者均完成了“国际前列腺症状评分”(IPSS)的存储部分,IPSS-QOL的生活质量部分和“膀胱过度​​活动问卷”(OABq)的形式和评分被计算。手术后,将病例随机分为5组,对第1组给予抗炎药,对第2组给予抗溶血药,对第3组给予抗胆碱能,对第4组给予抗胆碱药,作为对照组,不对第5组给予其他药物。在手术的第四周,IPSS,IPSS-QOL和OABq表格再次填写完毕,并将得分与之前的得分进行比较。结果:在评估所有病例后,应用双J支架的患者的IPSS,IPSS-QOL和OABq评分在统计学上显着高于手术。与对照组相比,使用双J支架的病例显示出更高的IPSS,IPSS-QOL和OABq评分,没有一种药物能够阻止这种增加。解释:在应用输尿管支架的情况下,LUTS的频率增加,只要支架留在体内,不适感就会持续。

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