In the present work, the effect of bed expansion on BSA adsorption on Amberlite IRA 410 ion-exchange resin was studied. The hydrodynamic behavior of an expanded bed adsorption column on effects of the biomolecules and salt addition and temperature were studied to optimize the conditions for BSA recovery on ion-exchange resin. Residence time distribution showed that HEPT, axial dispersion and the Pecletl number increased with temperature and bed height, bed voidage and linear velocity. The binding capacity of the resin increased with bed height. The Amberlite IRA 410 ion-exchange showed an affinity for BSA with a recovery yield of 78.36 % of total protein.
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机译：在本工作中，研究了床膨胀对Amberlite IRA 410离子交换树脂吸附BSA的影响。研究了膨胀床吸附塔对生物分子，盐添加和温度的影响的流体力学行为，以优化在离子交换树脂上回收BSA的条件。停留时间分布表明，HEPT，轴向色散和Pecletl数随温度和床高，床空隙度和线速度的增加而增加。树脂的结合能力随床高而增加。 Amberlite IRA 410离子交换显示出对BSA的亲和力，回收率占总蛋白的78.36％。
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