Often overlooked neuropsychiatric syndromes in Parkinson’s disease

摘要

Parkinson’s disease (PD) is a subcortical disorder that eventually spreads to the cortex. There is a wide variation in the global incidence and prevalence of PD. The disease usually presents in patients over the age of 65, although 5% of cases are under the age of 40 at the time of diagnosis. PD has a high prevalence of psychiatric co-morbidity. In this article, written with general neurologists and psychiatrists in mind, the main features and pathology of PD will be briefly outlined followed by a review of the epidemiology, aetiology, clinical features, and treatment of other often overlooked neuropsychiatric syndromes associated with PD. Close liaison between neurologists and psychiatrists is recommended in order to optimize treatment.