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Hemodynamics study of a multilayer stent for the treatment of aneurysms

机译:多层支架治疗动脉瘤的血流动力学研究

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Background The changes of hemodynamics caused by the implantation of multilayer stent (MS) have significant effects for aneurysm sac. Methods Comparisons of 3D numerical models with/without a MS in an abdominal aortic aneurysm with a 90° branch vessel were numerically studied from the viewpoint of hemodynamics. Results The results showed that: (1) The flow fields and Wall Shear Stress (WSS) are changed dramatically after MS implantation. The velocity of the blood flow in aneurysm sac decreases significantly and the regions of low-WSS increase. These help thrombus formation; (2) The pressure in aneurysm slightly decreases and keeps close to the normal level of blood pressure, however the risk of aneurysm enlargement or even rupture still exists; (3) The flux and the velocity in branch artery are reduced by about half after MS implantation. Due to the implantation of MS, the changes in the flow field causes the decrease of pressure/WSS in aneurysm sac and the blood flow in branch vessel. Conclusions The implantation of MS into abdominal artery results in more low-WSS regions inside aneurysm which induces thrombus formation. The pressure is reduced slightly means the risk of aneurysm rupture exists.
机译:背景技术多层支架(MS)植入引起的血流动力学变化对动脉瘤囊具有重大影响。方法从血液动力学的角度,对具有/不具有MS的3D数值模型在具有90°分支血管的腹主动脉瘤中进行比较研究。结果结果表明:(1)MS植入后,流场和壁剪切应力(WSS)发生了显着变化。动脉瘤囊中的血流速度明显降低,低WSS区域增加。这些有助于血栓形成; (2)动脉瘤内的压力略有下降并保持在正常血压水平,但仍存在动脉瘤增大甚至破裂的风险; (3)MS植入后,分支动脉的通量和速度降低了大约一半。由于MS的植入,流场的变化导致动脉瘤囊内压力/ WSS的降低以及分支血管的血流减少。结论将MS植入腹动脉可导致动脉瘤内部出现更多低WSS区域,从而引起血栓形成。压力稍微降低意味着存在动脉瘤破裂的风险。

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