High concentrations of KCl release noradrenaline from noradrenergic neurons in the rat anococcygeus muscle

C.b.l. Araujo; L.m. Bendhack

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High concentrations of KCl release noradrenaline from noradrenergic neurons in the rat anococcygeus muscle

机译：高浓度的KCl从大鼠无球藻肌肉中的去甲肾上腺素能神经元释放去甲肾上腺素

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The aim of the present study was to investigate the effects of high concentrations of KCl in releasing noradrenaline from sympathetic nerves and its actions on postsynaptic alpha-adrenoceptors. We measured the isotonic contractions induced by KCl in the isolated rat anococcygeus muscle under different experimental conditions. The contractile responses induced by KCl were inhibited by alpha-adrenoceptor antagonists in 2.5 mM Ca2+ solution. Prazosin reduced the maximum effect from 100 to 53.9 ± 10.2% (P

机译：本研究的目的是研究高浓度的氯化钾在从交感神经中释放去甲肾上腺素的作用及其对突触后α-肾上腺素受体的作用。我们在不同的实验条件下测量了氯化钾在离体大鼠无球藻肌肉中诱导的等渗收缩。在2.5 mM Ca2 +溶液中，α-肾上腺素受体拮抗剂抑制了KCl诱导的收缩反应。哌唑嗪的最大作用从100降低至53.9±10.2％（P

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《Brazilian Journal of Medical and Biological Research》 |2003年第1期|共8页
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C.b.l. Araujo; L.m. Bendhack;
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1. High concentrations of KCl release noradrenaline from noradrenergic neurons in the rat anococcygeus muscle [J] . Araujo C.B.L., Bendhack L.M. Brazilian Journal of Medical and Biological Research . 2003,第1期

机译：高浓度的KCl从鼠肌肉中从诺拉肾上腺素神经元释放去甲肾上腺素
2. Opposing local effects of endocannabinoids on the activity of noradrenergic neurons and release of noradrenaline: Relevance for their role in depression and in the actions of CB1 receptor antagonists [J] . KirillyE., HunyadyL., BagdyG. Journal of neural transmission . 2013,第1期

机译：对抗内源性大麻素对去甲肾上腺素能神经元活性和去甲肾上腺素释放的局部作用：与它们在抑郁症和CB1受体拮抗剂作用中的作用有关
3. Opposing local effects of endocannabinoids on the activity of noradrenergic neurons and release of noradrenaline: relevance for their role in depression and in the actions of CB1 receptor antagonists [J] . E. Kirilly, L. Hunyady, G. Bagdy Journal of Neural Transmission . 2013,第1期

机译：对抗内源性大麻素对去甲肾上腺素能神经元活性和去甲肾上腺素释放的局部作用：与它们在抑郁症中的作用以及CB1受体拮抗剂的作用有关
4. T cells affect central and peripheral noradrenergic mechanisms and neurotrophin concentration in the spleen and hypothalamus [C] . Jamela Jouda, Johannes Wildmann, Martin Schfer, International Society for Neuroimmunomodulation . 2012

机译：T细胞影响脾脏和下丘脑中的中枢和外周诺肾上腺素能机制和神经养素浓度
5. The role of brainstem noradrenergic neurons in communicating steroid hormone signals to luteinizing hormone -releasing hormone neurons [D] . Curran, Meredith Ames 2001

机译：脑干去甲肾上腺素能神经元在类固醇激素信号传递至促黄体激素释放激素神经元中的作用
6. Facilitation of noradrenaline release from sympathetic nerves in rat anococcygeus muscle by activation of prejunctional beta-adrenoceptors and angiotensin receptors. [O] . C. G. Li, H. Majewski, M. J. Rand 1988

机译：通过激活结前β-肾上腺素受体和血管紧张素受体促进大鼠肾小球菌肌中交感神经释放去甲肾上腺素。
7. High concentrations of KCl release noradrenaline from noradrenergic neurons in the rat anococcygeus muscle [O] . C.B.L. Araujo, L.M. Bendhack 2003

机译：高浓度的KCl从大鼠anococcygeus肌肉中的去甲肾上腺素能神经元释放去甲肾上腺素

High concentrations of KCl release noradrenaline from noradrenergic neurons in the rat anococcygeus muscle

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