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Non-adherence to anti-tuberculosis treatment, reasons and associated factors among TB patients attending at Gondar town health centers, Northwest Ethiopia

机译:埃塞俄比亚西北部贡达尔镇卫生院的结核病患者不坚持抗结核治疗的原因,相关因素

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Abstract ObjectiveThe aim of this study was to assess the prevalence of non-adherence to anti-tuberculosis treatment, reasons and associated factors among TB patients attending at Gondar town health centers.ResultA total of 314 participants were included with the response rate of 97.5%. The mean age of participants was 35.94 (SD?±?13.83) years. The overall rate of non-adherence to anti-TB treatment was 21.2% (95% CI 17.2, 26.1). Continuation phase of treatment (AOR?=?2.27, 95% CI (1.54, 5.94)), presence of more than one co-morbidity (AOR?=?6.22; 95% CI (2.21, 17.48)), poor knowledge about TB and anti-TB therapy (AOR?=?4.11; 95% CI 1.57, 10.75), poor patient-provider relationship (AOR?=?4.60, 95% CI 1.63, 12.97), and alcohol intake (AOR?=?5.03; 95% CI 1.54, 16.40) were significantly associated with non-adherence. Forgetting 40 (23.1%), Being busy with other work 35 (20.2%), and being out of home/town 24 (13.9%) were the major reasons of participants for interruption of taking anti-TB medications.
机译:摘要目的本研究旨在评估贡达镇卫生院结核病患者对抗结核治疗药物不依从的患病率,原因和相关因素。结果共纳入314名参与者,应答率为97.5%。参与者的平均年龄为35.94(SD±13.83)岁。不坚持抗结核治疗的总发生率为21.2%(95%CI 17.2,26.1)。治疗的持续阶段(AOR≥2.27,95%CI(1.54,5.94)),存在一种以上合并症(AOR≥6.22; 95%CI(2.21,17.48)),对结核病的了解较差抗结核治疗(AOR≥4.11; 95%CI 1.57,10.75),患者与医患关系差(AOR≥4.60、95%CI 1.63、12.97)和酒精摄入(AOR≥5.03; 95%CI 1.54,16.40)与不依从性显着相关。参加者中断服用抗结核药物的主要原因是:忘记40(23.1%),忙于其他工作35(20.2%)和出门在外24(13.9%)。

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