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Factors predicting home medication management practices among chronically ill older population of selected districts of Nepal

机译:预测尼泊尔某些地区慢性病老年人口家庭药物管理做法的因素

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Older population often have multiple and complex needs that are consequently challenged by the presence of polypharmacy, adverse drug reactions and drug-drug interaction. We aimed to determine home medication management practices (MMP) and its associated factors among chronically ill older population of selected districts of Nepal. A community based cross-sectional survey was conducted among 386 chronically ill older individuals from selected areas of Nepal between April to September 2016. Appropriateness of MMP was assessed through scores of questions using interview method. Multivariate logistic regression analysis using potential variables from bivariate analysis were used to determine factors affecting MMP. The overall home MMP was mostly inappropriate (80.1%). Most participants had multiple prescribers for single disease (202, 52.3%) and inappropriate medication storage (188, 48.7%). Though the majority of them had drug administration schedule (378, 97.9%), expired medicines were also used (2, 0.5%). Regression analysis showed less than one year duration of disease (odds ratio [OR]?=?3.901, 95% confidence interval [CI]?=?1.528 to 9.959, P?=?0.004), 1–2?years duration of disease (OR?=?2.415, 95% CI?=?1.210 to 4.821, P?=?0.012) and smokers (OR?=?2.025, 95% CI?=?1.036 to 3.956, P?=?0.039) as the major factors affecting appropriate home MMP. The home MMP was associated with duration of disease and smoking status among chronically ill older patients living in selected districts of Nepal. Proper counselling and monitoring of such patients might be necessary to improve the practice.
机译:老年人口往往有多种复杂需求,因此受到多药店,药物不良反应和药物相互作用的挑战。我们旨在确定尼泊尔选定地区的慢性病老年人群中的家庭药物管理规范(MMP)及其相关因素。在2016年4月至9月之间,对来自尼泊尔选定地区的386名慢性病老年人进行了基于社区的横断面调查。MMP的适当性通过使用访谈方法的问题分数进行评估。使用来自双变量分析的潜在变量进行多因素逻辑回归分析来确定影响MMP的因素。整个家庭的MMP大多不合适(80.1%)。大多数参与者针对单一疾病(202,52.3%)和不适当的药物存储(188,48.7%)有多个处方。尽管其中大多数都有给药时间表(378次,占97.9%),但也使用了过期药物(2次,占0.5%)。回归分析显示疾病持续时间少于一年(赔率[OR]?=?3.901,95%置信区间[CI]?=?1.528至9.959,P?=?0.004),病程为1-2年(OR≥2.415,95%CI≥1.210至4.821,P≥0.012)和吸烟者(OR≥2.025,95%CI≥1.036至3.956,P≥0.039)。影响适当家庭MMP的主要因素。居住在尼泊尔选定地区的慢性病老年患者的家庭MMP与疾病持续时间和吸烟状况有关。可能需要对此类患者进行适当的咨询和监视,以改善治疗方法。

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