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Morbidity, life style and psychosocial situation in cancer survivors aged 60-69 years: results from The Nord-Tr?ndelag Health Study (The HUNT-II Study)

机译:60-69岁癌症幸存者的发病率,生活方式和社会心理状况:Nord-Tr?ndelag健康研究(HUNT-II研究)的结果

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Background Due to considerable health status differences in the elderly population, research limited to narrow age-spans might be an advantage. In this population-based controlled study we compare short-term (Methods Among 9,089 individuals aged 60-69 who participated in HUNT-2, 334 had been diagnosed with invasive primary cancer from 1 month to 42 years before HUNT-2 according to CRN and self-report. An overall random sample of controls without cancer five times larger than the sample of cases (N = 1,670) were drawn from the parent cohort. Results The cancer sample comprised 128 STS and 206 LTS. For most variables no significant differences were observed between LTS and STS. LTS were significantly more women, and cases with gynaecological cancer, with physical impairment and more thyroid diseases compared to STS. When comparing all the survivors with controls, the survivors showed significantly higher rate of pensioning, decreased self-rated health, more physical impairment and thyroid diseases, daily use of medication and psychotropics and higher level of anxiety and Framingham Risk score. Multivariate logistic regression analysis showed that increasing age, being female, physical impairment and thyroid diseases all were significantly associated with being survivor versus controls. Conclusion STS and LTS showed mostly similar situation. Compared to controls, the survivors reported somewhat poorer physical and mental health, but these differences were of doubtful clinical significance.
机译:背景技术由于老年人的健康状况差异很大,因此仅限于狭窄年龄段的研究可能是一个优势。在这项基于人群的对照研究中,我们比较了短期(方法)。根据CRN和从父母队列中抽取了没有癌症的对照组的整体随机样本作为病例数的五倍(N = 1,670)结果癌症样本包括128个STS和206个LTS。在LTS和STS之间观察到,与STS相比,LTS的女性,患有妇科癌症,身体受损和甲状腺疾病的患者明显更多;当将所有幸存者与对照组进行比较时,幸存者的退休金率显着提高,自我评价降低健康,更多的身体障碍和甲状腺疾病,每天使用药物和精神药物以及更高的焦虑和Framingham风险评分水平。分析表明,年龄增长,女性,身体障碍和甲状腺疾病与存活者和对照组显着相关。结论STS和LTS的情况大致相似。与对照组相比,幸存者的身心健康状况略差,但这些差异具有可疑的临床意义。

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