Efeito antiproliferativo do extrato hidroalcoólico de Hymenaea stigonocarpa Mart. ex Hayne (Fabaceae, Caesalpinioideae) sobre as células meristemáticas de raízes de Allium cepa L

摘要

http://dx.doi.org/10.5007/2175-7925.2015v28n1p45 This study evaluates the hydroalcoholic extract obtained from the cork cambium of Hymenaea stigonocarpa (jatobá-do-cerrado) on the meristematic cells of Allium cepa roots, at 3 concentrations, 0.5, 1.0, and 1.5 mg/mL, and 2 exposure times, 24 h and 48 h. The slides were made through the crushing technique. Cells were analyzed throughout the cell cycle, totaling 5,000 for each control and concentration group. We found that the 3 concentrations significantly decreased the cell division rate at the exposure time of 48 h when compared to their respective controls. The mitotic index of the exposure time of 48 h was statistically different when compared to the cell division rate of the exposure time of 24 h for all concentrations. The number of cell abnormalities observed was not statistically significant by means of the chi-square test used. Therefore, under the conditions analyzed, the 3 concentrations tested for the cork cambium of jatobá-do-cerrado significantly decreased, in statistical terms, the cell division rate in the meristematic cells of A. cepa roots. ?