Prevalence of HBV-DNA Among HBsAg Positive Patients in Southeastern Region of Turkey by PCR

摘要

Background/Aims:Although hepatitis B virus (HBV) infections are a major health problem in Turkey, there is little information about prevalence of HBV-DNA that real indicator of infectious virion of HBV in Southeast of Turkey. The aim of this study was to investigate prevalence of HBV-DNA participated in dane particle of HBV instead of HBsAg in our region. Methods: We studied with serum of 132 HBsAg positive patients. For detection of HBV-DNA in serum, high sensitive polymerase chain reaction (PCR) technique was used. Results: From the 132 HBsAg positive patients, HBV-DNA could be amplified in the serum of 40 patients (30.30%). Conclusion: Generally for hepatitis B infection prevalence, HBsAg marker has been used in our region. By this study HBV-DNA prevalence was exposed for our region and these results may give right information about circumstance of Hepatitis infection because of infectious virion.