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The Effect of Carbon Monoxide on the Exergy Behavior of the Lungs

机译:一氧化碳对肺本能行为的影响

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The present work evaluates the impact of carbon monoxide (CO) inhalation on the human lung’s exergy behavior by considering different levels of intoxication and amounts of hemoglobin. Its impact is significant because CO is one of the most common air pollutants in cities and an increase in destroyed exergy may be correlated with lifespan reduction or the malfunctioning of certain human organs. An evaluation of the severity of intoxication as a function of city altitude may intensify the hazard associated with carbon monoxide. A computational model of human lungs obtained from the literature was used to calculate the concentrations of oxygen (O 2 ), carbon monoxide (CO), and carbon dioxide (CO 2 ) in the respiratory system. With the purpose of better evaluating the different levels of CO intoxication and hemoglobin concentration (which is a function of acclimatization time and some pathologies, such as anemia), a model calculating exergy efficiency for the lungs was proposed. From this model, it was possible to conclude that a higher level of intoxication is associated with lower exergy efficiency values. When associated with carbon monoxide intoxication, higher hemoglobin levels also result in lower efficiency. Eventually, a comparison between previous studies and the current study was carried out, regarding the method employed to calculate the exergy destroyed in the lungs, considering not only gas transport, but also hemoglobin concentration and its reaction with the gases from a second law perspective.
机译:目前的工作通过考虑不同程度的中毒程度和血红蛋白量来评估一氧化碳(CO)吸入对人肺本能行为的影响。它的影响非常重要,因为一氧化碳是城市中最常见的空气污染物之一,被破坏的火用增加可能与寿命缩短或某些人体器官功能异常有关。根据城市海拔高度对中毒严重程度进行评估可能会加剧与一氧化碳有关的危害。从文献中获得的人肺的计算模型用于计算呼吸系统中氧气(O 2),一氧化碳(CO)和二氧化碳(CO 2)的浓度。为了更好地评估不同程度的CO中毒和血红蛋白浓度(这是适应时间和某些疾病(如贫血)的函数),提出了一种计算肺部火用效率的模型。从该模型可以得出结论,较高的中毒水平与较低的火用效率值相关。当与一氧化碳中毒相关时,较高的血红蛋白水平也会导致较低的效率。最终,在以前的研究与当前的研究之间进行了比较,关于计算在肺中被破坏的本能的方法,不仅考虑了气体传输,而且还从第二定律的角度考虑了血红蛋白浓度及其与气体的反应。

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