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Why Imatinib is by Far the Best Drug to Treat Chronic Myeloid Leukemia?

机译:为什么迄今为止伊马替尼是治疗慢性粒细胞白血病的最佳药物?

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The objective of chronic myeloid leukemia treatment is to remove the platelets that contain the strange BCR-ABL gene that causes the high number of infected platelets. For the vast majority, it's unrealistic to dispose of every sick cell, yet treatment can accomplish a long haul remission of the disease. The meds utilized for patients with ceaseless (Chronic) stage interminable myelogenous leukemia (CML) go for postponing the onset of the quickened or blastic phase. This has generally incorporated a myelosuppressive operator to accomplish hematologic abatement, yet more compelling medications-progressively, interferon Alfa then and focused on treatment with tyrosine kinase inhibitors, for example, imatinib mesylate, have increased more noteworthy significance. Imatinib is a protein-tyrosine kinase inhibitor. It works by keeping the development of malignancy cells.
机译:慢性粒细胞白血病的治疗目标是去除含有引起大量感染血小板的奇怪BCR-ABL基因的血小板。对于绝大多数人来说,处置每个患病细胞是不现实的,但是治疗可以使疾病长期治愈。患有不间断(慢性)阶段可发作的骨髓性白血病(CML)的患者使用的药物可延缓快速或成骨期的发作。通常,它已合并了骨髓抑制操作员以完成血液学减轻,但更引人注目的药物-逐渐发展,然后干扰素Alfa并专注于酪氨酸激酶抑制剂(例如甲磺酸伊马替尼)的治疗具有更显着的意义。伊马替尼是一种蛋白质酪氨酸激酶抑制剂。它通过保持恶性细胞的发育而起作用。

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