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Cytotoxicity and DNA double-strand breaks in human gingival fibroblasts exposed to eluates of dental composites

机译:暴露于牙科复合材料洗脱液的人牙龈成纤维细胞的细胞毒性和DNA双链断裂

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摘要

Objective. Previously, single composite components were used to study cytotoxicity and induction of DNA double-strand breaks (DNA-DSBs) of dental composite resins. In the present study, cytotoxicity and induction of DNA-DSBs in human gingival fibroblasts (HGFs) were investigated with dental composite eluates consisting of multiple components. The eluates were qualified and quantified.
机译:目的。以前,单一复合材料成分用于研究牙科复合树脂的细胞毒性和DNA双链断裂(DNA-DSB)的诱导。在本研究中,使用由多种成分组成的牙科复合洗出液研究了人牙龈成纤维细胞(HGF)中DNA-DSB的细胞毒性和诱导作用。对洗脱液进行定性和定量。

著录项

  • 来源
    《Dental materials》 |2018年第2期|201-208|共8页
  • 作者单位

    Ludwig Maximilians Univ Munchen, Univ Hosp, Dept Conservat Dent & Periodontol, Munich, Germany;

    Ludwig Maximilians Univ Munchen, Univ Hosp, Dept Conservat Dent & Periodontol, Munich, Germany;

    Ludwig Maximilians Univ Munchen, Dept Orthodont, Goethestr 70, D-80336 Munich, Germany;

    Ludwig Maximilians Univ Munchen, Univ Hosp, Dept Conservat Dent & Periodontol, Munich, Germany;

    Ludwig Maximilians Univ Munchen, Univ Hosp, Dept Conservat Dent & Periodontol, Munich, Germany;

    Ludwig Maximilians Univ Munchen, Univ Hosp, Dept Conservat Dent & Periodontol, Munich, Germany;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    DNA double-strand breaks; gamma-H2AX; Multiple components; Elution; Cytotoxicity; Genotoxicity; TEGDMA; Culture medium; DMEM;

    机译:DNA双链断裂;γ-H2AX;多组分;洗脱;细胞毒性;基因毒性;TEGDMA;培养液;DMEM;
  • 入库时间 2022-08-18 03:46:22

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