Regioselective Transesterifications of Cyclohexanone Derivatives Containing β-Keto and Malonic Ester Moieties

摘要

The cyclohexanone derivatives 1-6 containing β-ketoester and α-disubstituted malonic ester moieties in the same molecule were found to undergo regioselective transesterifications with benzyl al- cohol giving exclusively β-keto benzyl esters. On the contrary, the acyclic derivatives 9, 10 containing β-ketoester an α-monosubse- ituted malonic ester groups gave mixtures of transesterified prod- ucts under the same reaction conditions.